The Hammers defender limped off after half an hour with an ankle damage, following a problem by Brentford’s Christian Norgaard.
Zouma, 27, was despatched for a scan on Monday, forward of Thursday’s essential Europa League quarter-final, second leg, in opposition to Lyon on Thursday.
West Ham are degree within the tie at 1-1 however will already be with out left-back Aaron Cresswell following his controversial pink card on the London Stadium final Thursday.
“Kurt has twisted his ankle,” mentioned supervisor David Moyes. “We don’t understand how dangerous it’s.
“We’ll get him checked. Coming off is just not a superb signal however hopefully it’s not too dangerous.”
The Hammers had been on the again foot from the off in opposition to the Bees, with Moyes conceding that the taxing Europa League schedule was taking its toll on his skinny squad.
“Maybe Thursday-Sunday caught up with us a bit of bit right now,” mentioned the Scot. “We lacked the depth we’ve received in our common performances. We hardly made any possibilities.”
West Ham switched off in permitting Bryan Mbuemo to open the scoring from a throw-in routine minutes into the second half, earlier than leaving the Bees ahead free to tee up Ivan Toney to double the lead quickly after.
West Ham had been no less than capable of welcome again Vladimir Coufal for his first begin since present process surgical procedure for a hernia earlier this season.
The Czech full-back has revealed he had been battling the damage since final summer season’s European Championship.
“I used to be struggling because the begin of the season,” Coufal advised Standard Sport.
“It began within the Euros however I didn’t listen as a result of I believed it will move. After it was extra severe and extra severe and I used to be nonetheless enjoying.
“I labored actually arduous for six weeks.
“The first prediction was to return after six weeks. After 5 weeks I used to be able to play. Professor Ernest Schilders did an incredible job with the surgical procedure. Rich and George sorted me and did an incredible job. I have to thank them as a result of they sorted me like their youngsters.”
After Arsenal and Manchester United misplaced on Saturday, West Ham missed probability to take benefit within the race for Europe, however Coufal insists they received’t surrender their struggle.
“Top 4 is extra of a dream than a purpose,” mentioned Coufal.
“Our actual purpose must be prime six or to get into Europe subsequent season, whichever manner we will do this. It doesn’t matter how we attain it however our purpose is to achieve European soccer. [The Brentford defeat] doesn’t change our confidence.
“We have a superb squad, a really sturdy squad. We simply possibly want some adjustments, we’ll see. I’m not the supervisor so it’s as much as him. We are going to do all the pieces to convey a semi-final to London Stadium.”