PDS-08™ displays Seed’s mission to deliver scientific rigor, efficacy, and novel knowledge era to the worldwide class of probiotics
LOS ANGELES, April 13, 2022 /PRNewswire/ — Seed, the microbiome science firm pioneering clinically and scientifically studied next-generation probiotics, right now launched its first pediatric innovation, PDS-08™ Pediatric Daily Synbiotic, a clinically studied, two-in-one powdered synbiotic formulated for youngsters and adolescents (ages 3 to 17) with 9 probiotic strains and a fiber-based prebiotic. This launch follows Seed’s award-winning flagship synbiotic for adults, DS-01™ Daily Synbiotic, and extends the corporate’s mission to steward the subsequent era of probiotics to the kids’s well being market.
Over the previous decade, analysis has illuminated the numerous position of the microbiome in a creating baby and the way components like weight-reduction plan, train, atmosphere, use of antibiotics, sleep, and hygiene can affect crucial home windows of improvement and inform their systemic well being by way of maturity. Alongside these components, probiotics for adults and pediatrics have large potential for affect, although acceptable skepticism and confusion stay because of the plethora of unvalidated advantages marketed right now.
“With a better understanding of the pediatric microbiome—and the way probiotic interventions can be utilized to assist it—we are able to ship on the promise of probiotics by advancing clinically studied interventions with validated doses and protocols, coupled with improved outcomes for infants and youngsters,” mentioned Dr. James Versalovic, Pathologist-in-Chief at Texas Children’s Hospital, Director of Texas Children’s Microbiome Center, and Seed Health Scientific Board member.
Science-First Approach to Children’s Probiotics
PDS-08™ is a clinically studied probiotic and prebiotic formulated with 9 probiotic strains—every with revealed dose-response knowledge—and mixed-chain prebiotic fibers to preferentially assist probiotic exercise within the GI tract. PDS-08™ can be engineered to optimize probiotic survivability and stability by way of digestion, with supply know-how that safeguards choose strains from abdomen acid, enzymes and bile salts.
In addition to 18 scientific research validating strain-specific benefits throughout intestine barrier integrity, gut-immune operate, dermatological well being and respiratory well being, PDS-08™ was evaluated in a 12-week, randomized, placebo-controlled scientific trial, demonstrating assist for gastrointestinal operate and wholesome regularity in a pediatric inhabitants. The trial evaluation employed state-of-the-art bioinformatics from the Mason Lab, which focuses on next-generation sequencing, practical genomics, and algorithms to elucidate human illness mechanisms.
“Over the final decade, the rate of microbiome science discoveries that rework our understanding of every part and side of a kid’s well being has been unprecedented,” remarked Raja Dhir, Co-CEO and Co-Founder of Seed. “With superior bioinformatics, distinctive scientific endpoints, and novel bioinformatics, we now have a deeper understanding of the pediatric microbiome to unlock novel functions for probiotics.”
Key PDS-08TM scientific insights and formulation highlights:
- Easy, frequent bowel actions, with out stimulants
Children taking PDS-08TM and experiencing intermittent constipation (lower than 5 weekly bowel actions) noticed a rise in common, wholesome weekly BMs—a big discovering contemplating as many as 30% of children wrestle with intermittent, constipation-related GI misery.
- Benefits in and past the intestine
PDS-08™ is formulated with strains clinically studied in a pediatric inhabitants to assist digestive well being, intestine barrier integrity, gut-immune operate, and dermatological and respiratory well being.
- Advanced respiratory well being assist
PDS-08™ is the primary multi-strain synbiotic to incorporate two pioneering strains clinically validated to assist respiratory well being in kids, together with wholesome respiratory tract operate and a wholesome response to seasonal airborne particles.
- Novel prebiotic to assist bridge the fiber hole
95% of youngsters and adults within the U.S. don’t attain their every day advisable fiber consumption. PDS-08™’s novel prebiotic mix affords 5 grams of prebiotic fiber per serving to assist bridge the fiber hole and complement a nutritious diet.
- Increased Bifidobacterium
As demonstrated through metagenomic shotgun sequencing, PDS-08™ was proven to considerably enrich Bifidobacterium (native, commensal micro organism linked to the upkeep and enchancment of digestive and immune operate) within the pediatric intestine microbiome.
- Exceptionally well-tolerated
Children taking PDS-08™ had no noticed uncomfortable side effects or GI misery reminiscent of abdomen ache, bloating, fuel, or diarrhea, as generally reported with many fiber-based dietary dietary supplements, probiotics, and high-dose fermentable prebiotics.
Setting a New Standard in Children’s Probiotics
“While there’s proof to assist probiotic intervention for choose pediatric situations, the advertising and marketing and commercialization are sometimes forward of the science. In a sea of hyperbolic claims and misinformation, choosing the proper probiotic in your baby can really feel paralyzing,” defined Ara Katz, Co-CEO and Co-Founder. “With PDS-08™, we got down to develop a clinically validated pediatric innovation to raise the class and provide a science-first choice mother and father and pediatricians can belief.”
PDS-08™ is the corporate’s first client launch because the announcement of its $40 million Series A final 12 months and marks Seed’s entry into the fast-growing world kids’s well being and wellness market. In collaboration with a Scientific Board of main microbiome researchers, clinicians, and tutorial companions, Seed’s platform interprets breakthrough science throughout a pipeline of functions in gastrointestinal and digestive well being, girls’s well being, pores and skin and oral care, pediatrics, psychological well being, metabolic operate, and diet.
For pediatricians, mother and father, and caregivers—seed.com/PDS08
- Available by subscription for $39.99/month at seed.com.
- Sustainably delivered with a refill system comprised of novel biomaterials.
- First month features a free, refillable BacTrac™ container with a built-in every day monitoring system, so mother and father by no means miss a day.
- No refrigeration required.
- Free from sugar, synthetic colorants, flavors, preservatives, and 14 classes of allergens.
- Over 50 quality-assurance and quality-control checkpoints, together with purity, efficiency and survivability validation, whole-genome sequencing and warmth, humidity and allergen testing.
About Seed Health | Seed
Seed Health is a microbiome science firm pioneering improvements in probiotics and dwelling medicines to affect human and planetary well being. Founded to understand the potential of microbes, our platform permits the interpretation of breakthrough science throughout a portfolio encompassing each indication-specific and preventive functions for gastrointestinal and digestive well being, girls’s well being, pores and skin and oral care, pediatrics, psychological well being, metabolic operate, and diet. Our client improvements are commercialized beneath Seed® with a mission to deliver much-needed precision, efficacy, training, and perspective-shifting science communication to the worldwide class of probiotics. Environmental analysis is performed beneath SeedLabs, which was based to develop novel bacterial interventions to boost biodiversity and restore ecosystems impacted by human exercise.
LUCA Biologics, co-founded with Dr. Jacques Ravel, develops dwelling medicines concentrating on the vaginal microbiome for urogenital and reproductive well being.
Media contact: Elle Communications, [email protected]
SOURCE Seed Health