Review Finds Minimal Evidence That Dietary Supplements Lead to Weight Loss

A metanalysis of 315 medical trials of weight reduction dietary supplements and therapies revealed in Obesity discovered an absence of sturdy proof that dietary dietary supplements and different therapies assist adults shed pounds. According to the researchers, many of the research reviewed discovered that the dietary supplements analyzed didn’t produce weight reduction amongst customers.

The investigators carried out a scientific overview of the present literature utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses tips to guage the efficacy of dietary dietary supplements and different therapies for weight reduction in members aged 18 and older. Searches of Medline (Pubmed), Cochrane Library, Web of Science, CINAHL and Embase (Ovid) have been carried out to assemble knowledge.

The evaluation centered on 315 peer-reviewed, randomized-controlled trials and analyzed them for threat of bias, in the end classifying 52 research as low-risk of bias and enough to help efficacy. Of these 52 research, 16 have been discovered to display vital pre/put up intergroup variations in weight when in comparison with placebo. Weight loss throughout these research diversified from 0.3 kg to 4.93 kg.

“Our findings are vital for clinicians, researchers, and business alike as they counsel the necessity for rigorous analysis of merchandise for weight reduction,” mentioned John Batsis, MD, affiliate professor within the Division of Geriatric Medicine on the University of North Carolina (UNC) School of Medicine, and within the Department of Nutrition on the UNC Gillings School of Global Public Health, in a press launch. “Only then can we produce knowledge that enables clinicians to supply enter and recommendation with a better diploma of certainty to our sufferers.”

According to the examine authors, sufferers usually battle to lose or preserve weight both due to an absence of efficacy of current FDA-approved therapies or an absence of entry to well being care professionals who present remedies for weight problems. They mentioned that private and non-private entities ought to present satisfactory assets for weight problems administration. Further, regulatory authorities ought to critically look at the dietary complement business to cut back deceptive claims and halt the advertising and marketing of merchandise which have the potential to hurt sufferers.


Review reveals minimal, high-quality proof dietary dietary supplements result in weight reduction [news release]. EurekAlert; June 23, 2021. Accessed June 23, 2021.

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